[HTML][HTML] Role of cytokines in EGPA and the possibility of treatment with an anti-IL-5 antibody
T Isozaki, T Homma, H Sagara, T Kasama - Journal of Clinical Medicine, 2020 - mdpi.com
… is insufficient, the anti-interleukin-5 antibody mepolizumab can be … mediator of allergic
asthma and induces IL-5 and eotaxin/CCL11 … These associations led to the speculation that the …
asthma and induces IL-5 and eotaxin/CCL11 … These associations led to the speculation that the …
[HTML][HTML] Interleukin-5 in the pathophysiology of severe asthma
C Pelaia, G Paoletti, F Puggioni, F Racca… - Frontiers in …, 2019 - frontiersin.org
… and eotaxins were found in induced sputum from patients experiencing acute asthma
exacerbations (… Binding interactions of human interleukin 5 with its receptor α subunit. Large scale …
exacerbations (… Binding interactions of human interleukin 5 with its receptor α subunit. Large scale …
The roles of IL-5 and anti-IL-5 treatment in eosinophilic diseases: Asthma, eosinophilic granulomatosis with polyangiitis, and eosinophilic chronic rhinosinusitis
H Nagase, S Ueki, S Fujieda - Allergology International, 2020 - jstage.jst.go.jp
… for severe asthma (Table 1) In our analysis, approximately 25% of patients with severe asthma
… We classified the patients with severe asthma (n ¼ 102) into four phenotypes based on …
… We classified the patients with severe asthma (n ¼ 102) into four phenotypes based on …
Relationship between various cytokines implicated in asthma
… that are often observed in asthma. Ultimately, these … of asthma. The main focus of this
review is to accentuate the relationship between various cytokines implicated in human asthma. …
review is to accentuate the relationship between various cytokines implicated in human asthma. …
[HTML][HTML] Study of serum interleukin 5 level and factors that impact on this level in Iraqi asthmatic children
RM Hameed, HAAN Abood, MM Ahmed… - Biomedical and …, 2019 - journals.lww.com
… , and immunological parameters of asthmatic children in interleukin-5 levels Further, in this
study, there was a significant difference in the IL-5 level in asthma patients depending on sex, …
study, there was a significant difference in the IL-5 level in asthma patients depending on sex, …
[HTML][HTML] IL-5 antagonism reverses priming and activation of eosinophils in severe eosinophilic asthma
J Luo, W Chen, W Liu, S Jiang, Y Ye, R Shrimanker… - Mucosal …, 2024 - Elsevier
… Expression of chemokine receptors in eosinophils and interleukin-5 levels in patients was not
… No significant difference was detected in eotaxin concentrations in EA, although eotaxin-2 …
… No significant difference was detected in eotaxin concentrations in EA, although eotaxin-2 …
Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic chronic obstructive pulmonary disease
M Fricker, VM McDonald, NA Winter, KJ Baines… - Allergy, 2021 - Wiley Online Library
… production of eosinophil chemokines including eotaxins CCL11 and CCL24. … severe asthma
vs mild to moderate and non-asthma controls; however similar to our study, no association …
vs mild to moderate and non-asthma controls; however similar to our study, no association …
Two cases of dupilumab-associated eosinophilic pneumonia in asthma with eosinophilic chronic rhinosinusitis: IL-5-driven pathology?
Y Nishiyama, T Koya, K Nagano, S Abe… - Allergology …, 2022 - jstage.jst.go.jp
… vascular cell adhesion protein 1 (VCAM-1), eotaxin, and periostin, which are strongly involved
in the … In both cases as previously reported,1 CCL26 (eotaxin-3) and periostin significantly …
in the … In both cases as previously reported,1 CCL26 (eotaxin-3) and periostin significantly …
IL‐5 receptor expression in lung fibroblasts: Potential role in airway remodeling in asthma.
K Bajbouj, R AbuJabal, L Sahnoon, R Olivenstein… - Allergy, 2023 - search.ebscohost.com
… Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics con…
model of atopic asthma: suppression by dexamethasone or anti- interleukin- 5 antibody. Am …
model of atopic asthma: suppression by dexamethasone or anti- interleukin- 5 antibody. Am …
[HTML][HTML] Treatment challenges in severe eosinophilic asthma: differential response to anti-IL-5 and anti-IL-5R therapy
A Bakakos, N Rovina, P Bakakos - International Journal of Molecular …, 2021 - mdpi.com
… It is clinically important to underline that eotaxin-1 cannot mobilize … since eotaxin-1 alone
can only lead to blood eosinophilia but not to tissue infiltration. On the contrary, blocking eotaxin…
can only lead to blood eosinophilia but not to tissue infiltration. On the contrary, blocking eotaxin…